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Answers tagged ankylosing spondylitis: Page 1 of 1
Julie from Calgary asks: Does a negative test rule out ankylosing spondylitis?
As of 2017, there are no definitive blood tests which can diagnose or rule out ankylosing spondylitis. HLA B27 is a genetic marker which is often found in patients with AS, but it is not required to make a diagnosis. Similarly, inflammatory markers in the blood may be elevated in AS, but may also be normal. To make a diagnosis of ankylosing spondylitis, or to rule it out, a patient should review their story with their physician or rheumatologist. The rheumatologist often will obtain further imaging, including x-rays or an MRI of the lower spine, to help ascertain a diagnosis.
Caroline from Scotland asks: Does Ankylosing Spondylitis affect joints besides the back?
While Ankylosing Spondylitis usually affects the back, it can affect other joints as well. Larger joint involvement is more common than smaller joints such as the hands or feet. Tendon involvement, particularly where the tendon attaches to the bone, can be seen.
Carolina from Calgary asks: My husband has AS and may be starting a TNF blocker. We were told once he starts it, he will be on it for life, even if he goes into complete remission because the worst thing to do with biologics is to start and stop them since it may increase immunity to it. So, if after a while he is free of symptoms, can he to try to wean off the med or does he have to take it for the rest of his life?
Assuming a good response to a biologic for ankylosing spondylitis or rheumatoid arthritis, one can always try to see if the disease will remain under control off medication, be it a biologic or traditional DMARD. There is a risk of the disease flaring of course, and there is a risk of not having as a good a response to the same medications a second time. However, many patients do this and most do not have problems restarting their medications again.
Joanne from Edmonton asks: I have had 6 episodes of iritis in the last 3 years. Based on the fact that I have had iritis my doctor has done blood work and said one level is slightly elevated. I am wondering if I should be referred to a rheumatologist for further investigation.
Iritis is an inflammatory disease of the iris, the coloured ring around your pupil. Iritis can occur for many different reasons, but can be associated with some rheumatic diseases, most commonly ankylosing spondylitis. It is not uncommon for an eye specialist to refer a patient with uveitis to a rheumatologist for further investigation when another underlying cause for iritis (also known as uveitis) cannot be found.