Jen from Edmonton asks: My methotrexate vial says “for intramuscular, intravenous, and intra-arterial use only”, but I am supposed to inject it subcutaneously. Should I be concerned?

Methotrexate use for rheumatic diseases, including rheumatoid arthritis, can be given as a tablet or injection.  For those receiving methotrexate by injection, self-injection is done subcutaneously – under the skin.  An intramuscular injection can also be done, although usually cannot be self-administered.  Methotrexate should not be put directly in a vein or artery for rheumatic diseases.  To learn more about how to do methotrexate self injections, visit our video here.

Posted: September 25, 2015

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