Vaccinations when taking DMARDs or Biologics Print Page

recommended-vaccinations-in-inflammatory-arthritis_commonnames_nov2016

a If patient has received Pneumovax-23 previously, administer Prevnar-13 at least 1 year later, followed by a Pneumovax-23 booster ³5 years after the first dose at age ³65.
b Despite the monograph statement that Zostavax II should not be administered at the same time as Pneumovax-23 due to potential for reduced immune response, this has not been found to be clinically important. Thus, either Prevnar-13 or Pneumovax-23 may be provided concomitantly with Zostavax II.
1 Ideally, provide ≥14 days before biologic initiation or wait >3 half-lives after stopping biologic therapy
2 Administer ≥4 weeks before biologic initiation or wait >3 half-lives and at least 1 month after stopping biologic therapy
3 To ensure minimal immunosuppression (reduce risk of infection) and optimal vaccine response: recommend waiting >3 half-lives after stopping biologics to give live vaccines. To ensure safety, guidelines recommend waiting 6mo after last dose of RTX & INFL.

biologic-halflife
4 Under compelling circumstances may be considered; consultation with infectious diseases physician recommended.
5 High-Risk Groups:
Hepatitis A: travel to, immigrants from, or residence in endemic countries of HAV; occupational exposure (i.e. health care professionals); infected family member or contacts; illicit drug users; men who have sex with men; chronic liver disease.
Hepatitis B: residents, immigrants, travelers, or close contact with individuals from HBV endemic areas; persons with lifestyle risks: illicit drug use (injectable or non-injectable), oral sex, men who have sex with men, other high risk sexual practices; chronic liver disease; chronic kidney disease; occupational exposure (i.e. health care professionals); frequent blood transfusions.
HPV: previous STI, number of partners, inconsistent condom use, men who have sex with men (not covered by public health)
Meningococcal: travellers to sub-Saharan Africa, Mecca, Saudi Arabia; laboratory or military personnel; close contact of a case of IMD or outbreak control, high risk medical conditions.



What is Rheumatology?

Rheumatologists see over 100 different types of diseases. We are known for seeing arthritis, however, we also see many other conditions.

Learn More

Find us on YouTube

Visit our YouTube channel and find a number of helpful videos to learn more about a range of topics relating to rheumatology.

Visit our YouTube Channel

Make a Donation

Support arthritis care in Alberta. Click the button below for more info, or to make a donation today.

Donate