MSM Print Page
Common Names: MSM, methyl sulfone
Scientific Names: Methylsulfonylmethane
Effectiveness: Currently lack reliable evidence, but some preliminary studies suggest possible benefit in OA.
Safety: Generally well tolerated when used in appropriate doses for up to 12 weeks; long term safety is unknown.
What is MSM?
- MSM, or methylsulfonylmethane, is a chemical found in some green plants, vegetables, fruits, grains, and certain animal products. MSM is a source of sulfur used to make certain amino acids in the body.
What it is it used for in people with rheumatic conditions?
- MSM has been used for the management of osteoarthritis to reduce joint pain and improve function.
How is it thought to work?
- Preliminary research suggests that MSM may reduce joint breakdown in animal models of osteoarthritis. It seems to reduce inflammation and act as an antioxidant.
Does it Work? What the Science Says:
|MSM 3 grams twice daily; 1.5 grams three times daily in combination with glucosamine||
What are possible side effects and what can I do about them?
- MSM is generally well tolerated when taken orally. Nausea, diarrhea, bloating, headache, fatigue, trouble sleeping, and reduced concentration have been reported.
- No interactions between MSM and other drugs, conditions, or natural health products have been reported. However, there is currently not enough evidence to fully assess the safety of MSM.
For more information about MSM, visit AlbertaRheumatology.com or consult your physician and pharmacist.